Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Col2a1  collagen, type II, alpha 1   (Synonyms: Col2, Col2a, Col2a-1, Del1, Lpk, M100413, M100856, Rgsc413, Rgsc856)
Results	Reference
1	J:98096 Aberg T, Rice R, Rice D, Thesleff I, Waltimo-Siren J, Chondrogenic potential of mouse calvarial mesenchyme. J Histochem Cytochem. 2005 May;53(5):653-63
1	J:153618 Ahrens MJ, Li Y, Jiang H, Dudley AT, Convergent extension movements in growth plate chondrocytes require gpi-anchored cell surface proteins. Development. 2009 Oct;136(20):3463-74
1	J:79879 Akiyama H, Chaboissier MC, Martin JF, Schedl A, De Crombrugghe B, The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6. Genes Dev. 2002 Nov 1;16(21):2813-28
1*	J:132390 Alexandrovich A, Qureishi A, Coudert AE, Zhang L, Grigoriadis AE, Shah AM, Brewer AC, Pizzey JA, A role for GATA-6 in vertebrate chondrogenesis. Dev Biol. 2008 Feb 15;314(2):457-70
1	J:309392 Amano K, Densmore MJ, Lanske B, Conditional Deletion of Indian Hedgehog in Limb Mesenchyme Results in Complete Loss of Growth Plate Formation but Allows Mature Osteoblast Differentiation. J Bone Miner Res. 2015 Dec;30(12):2262-72
1	J:310588 Amara CS, Fabritius C, Houben A, Wolff LI, Hartmann C, CaMKII Signaling Stimulates Mef2c Activity In Vitro but Only Minimally Affects Murine Long Bone Development in vivo. Front Cell Dev Biol. 2017;5:20
1	J:168583 Araldi E, Khatri R, Giaccia AJ, Simon MC, Schipani E, Lack of HIF-2alpha in limb bud mesenchyme causes a modest and transient delay of endochondral bone development. Nat Med. 2011 Jan;17(1):25-6; author reply 27-9
1	J:95024 Baffi MO, Slattery E, Sohn P, Moses HL, Chytil A, Serra R, Conditional deletion of the TGF-beta type II receptor in Col2a expressing cells results in defects in the axial skeleton without alterations in chondrocyte differentiation or embryonic development of long bones. Dev Biol. 2004 Dec 1;276(1):124-42
1	J:124680 Brugmann SA, Goodnough LH, Gregorieff A, Leucht P, Ten Berge D, Fuerer C, Clevers H, Nusse R, Helms JA, Wnt signaling mediates regional specification in the vertebrate face. Development. 2007 Sep;134(18):3283-95
1	J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21
1	J:232617 Chen Z, Yue SX, Zhou G, Greenfield EM, Murakami S, ERK1 and ERK2 regulate chondrocyte terminal differentiation during endochondral bone formation. J Bone Miner Res. 2015 May;30(5):765-74
1	J:327334 Choi KY, Lee SW, Park MH, Bae YC, Shin HI, Nam S, Kim YJ, Kim HJ, Ryoo HM, Spatio-temporal expression patterns of Runx2 isoforms in early skeletogenesis. Exp Mol Med. 2002 Dec 31;34(6):426-33
1	J:98427 Day TF, Guo X, Garrett-Beal L, Yang Y, Wnt/beta-Catenin Signaling in Mesenchymal Progenitors Controls Osteoblast and Chondrocyte Differentiation during Vertebrate Skeletogenesis. Dev Cell. 2005 May;8(5):739-50
1	J:230611 Dierker T, Bachvarova V, Krause Y, Li JP, Kjellen L, Seidler DG, Vortkamp A, Altered heparan sulfate structure in Glce(-/-) mice leads to increased Hedgehog signaling in endochondral bones. Matrix Biol. 2016 Jan;49:82-92
1	J:181901 Eitzinger N, Surmann-Schmitt C, Bosl M, Schett G, Engelke K, Hess A, von der Mark K, Stock M, Ucma is not necessary for normal development of the mouse skeleton. Bone. 2012 Mar;50(3):670-80
1*	J:92176 Ficker M, Powles N, Warr N, Pirvola U, Maconochie M, Analysis of genes from inner ear developmental-stage cDNA subtraction reveals molecular regionalization of the otic capsule. Dev Biol. 2004 Apr 1;268(1):7-23
1	J:85490 Fukushi J, Inatani M, Yamaguchi Y, Stallcup WB, Expression of NG2 proteoglycan during endochondral and intramembranous ossification. Dev Dyn. 2003 Sep;228(1):143-8
1	J:189063 Goodnough LH, Chang AT, Treloar C, Yang J, Scacheri PC, Atit RP, Twist1 mediates repression of chondrogenesis by beta-catenin to promote cranial bone progenitor specification. Development. 2012 Dec;139(23):4428-38
1	J:74145 Gori F, Schipani E, Demay MB, Fibromodulin is expressed by both chondrocytes and osteoblasts during fetal bone development. J Cell Biochem. 2001 Apr 2-27;82(1):46-57
1*	J:138379 Gu S, Wei N, Yu L, Fei J, Chen Y, Shox2-deficiency leads to dysplasia and ankylosis of the temporomandibular joint in mice. Mech Dev. 2008 Aug;125(8):729-42
1	J:245766 He F, Soriano P, Dysregulated PDGFRalpha signaling alters coronal suture morphogenesis and leads to craniosynostosis through endochondral ossification. Development. 2017 Nov 01;144(21):4026-4036
1	J:114686 Hinoi E, Bialek P, Chen YT, Rached MT, Groner Y, Behringer RR, Ornitz DM, Karsenty G, Runx2 inhibits chondrocyte proliferation and hypertrophy through its expression in the perichondrium. Genes Dev. 2006 Nov 1;20(21):2937-42
1*	J:130304 Hiraoka S, Furuichi T, Nishimura G, Shibata S, Yanagishita M, Rimoin DL, Superti-Furga A, Nikkels PG, Ogawa M, Katsuyama K, Toyoda H, Kinoshita-Toyoda A, Ishida N, Isono K, Sanai Y, Cohn DH, Koseki H, Ikegawa S, Nucleotide-sugar transporter SLC35D1 is critical to chondroitin sulfate synthesis in cartilage and skeletal development in mouse and human. Nat Med. 2007 Nov;13(11):1363-7
1	J:185618 Hojo H, Ohba S, Yano F, Saito T, Ikeda T, Nakajima K, Komiyama Y, Nakagata N, Suzuki K, Takato T, Kawaguchi H, Chung UI, Gli1 protein participates in Hedgehog-mediated specification of osteoblast lineage during endochondral ossification. J Biol Chem. 2012 May 18;287(21):17860-9
1	J:129305 Holst CR, Bou-Reslan H, Gore BB, Wong K, Grant D, Chalasani S, Carano RA, Frantz GD, Tessier-Lavigne M, Bolon B, French DM, Ashkenazi A, Secreted sulfatases Sulf1 and Sulf2 have overlapping yet essential roles in mouse neonatal survival. PLoS One. 2007;2(6):e575
1*	J:306544 Hyde G, Boot-Handford RP, Wallis GA, Col2a1 lineage tracing reveals that the meniscus of the knee joint has a complex cellular origin. J Anat. 2008 Nov;213(5):531-8
1*	J:171508 Ikegami D, Akiyama H, Suzuki A, Nakamura T, Nakano T, Yoshikawa H, Tsumaki N, Sox9 sustains chondrocyte survival and hypertrophy in part through Pik3ca-Akt pathways. Development. 2011 Apr;138(8):1507-19
1*	J:140470 Imuta Y, Nishioka N, Kiyonari H, Sasaki H, Short limbs, cleft palate, and delayed formation of flat proliferative chondrocytes in mice with targeted disruption of a putative protein kinase gene, Pkdcc (AW548124). Dev Dyn. 2008 Dec 18;238(1):210-222
1	J:153633 Ito T, Yadav N, Lee J, Furumatsu T, Yamashita S, Yoshida K, Taniguchi N, Hashimoto M, Tsuchiya M, Ozaki T, Lotz M, Bedford MT, Asahara H, Arginine methyltransferase CARM1/PRMT4 regulates endochondral ossification. BMC Dev Biol. 2009;9:47
1*	J:300574 Jiang Q, Qin X, Yoshida CA, Komori H, Yamana K, Ohba S, Hojo H, Croix BS, Kawata-Matsuura VKS, Komori T, Antxr1, Which is a Target of Runx2, Regulates Chondrocyte Proliferation and Apoptosis. Int J Mol Sci. 2020 Mar 31;21(7):2425
1	J:154905 Joeng KS, Long F, The Gli2 transcriptional activator is a crucial effector for Ihh signaling in osteoblast development and cartilage vascularization. Development. 2009 Dec;136(24):4177-85
1	J:58886 Johnson J, Shinomura T, Eberspaecher H, Pinero G, Decrombrugghe B, Hook M, Expression and localization of PG-Lb/epiphycan during mouse development. Dev Dyn. 1999 Dec;216(4-5):499-510
1	J:129783 Kaback LA, Soung do Y, Naik A, Smith N, Schwarz EM, O'Keefe RJ, Drissi H, Osterix/Sp7 regulates mesenchymal stem cell mediated endochondral ossification. J Cell Physiol. 2008 Jan;214(1):173-82
1	J:148688 Kahn J, Shwartz Y, Blitz E, Krief S, Sharir A, Breitel DA, Rattenbach R, Relaix F, Maire P, Rountree RB, Kingsley DM, Zelzer E, Muscle contraction is necessary to maintain joint progenitor cell fate. Dev Cell. 2009 May;16(5):734-43
1*	J:59287 Karp SJ, Schipani E, St-Jacques B, Hunzelman J, Kronenberg H, McMahon AP, Indian hedgehog coordinates endochondral bone growth and morphogenesis via parathyroid hormone related-protein-dependent and -independent pathways. Development. 2000 Feb;127(3):543-8
1	J:298035 Kelly NH, Huynh NPT, Guilak F, Single cell RNA-sequencing reveals cellular heterogeneity and trajectories of lineage specification during murine embryonic limb development. Matrix Biol. 2020 Jul;89:1-10
1	J:248885 Kikuchi M, Shimada M, Matsuzaka T, Ishii K, Nakagawa Y, Takayanagi M, Yamada N, Shimano H, Crucial Role of Elovl6 in Chondrocyte Growth and Differentiation during Growth Plate Development in Mice. PLoS One. 2016;11(7):e0159375
1	J:77683 Kobayashi T, Chung UI, Schipani E, Starbuck M, Karsenty G, Katagiri T, Goad DL, Lanske B, Kronenberg HM, PTHrP and Indian hedgehog control differentiation of growth plate chondrocytes at multiple steps. Development. 2002 Jun;129(12):2977-86
1	J:121700 Kolanczyk M, Kossler N, Kuhnisch J, Lavitas L, Stricker S, Wilkening U, Manjubala I, Fratzl P, Sporle R, Herrmann BG, Parada LF, Kornak U, Mundlos S, Multiple roles for neurofibromin in skeletal development and growth. Hum Mol Genet. 2007 Apr 15;16(8):874-86
1	J:107394 Le Goff C, Somerville RP, Kesteloot F, Powell K, Birk DE, Colige AC, Apte SS, Regulation of procollagen amino-propeptide processing during mouse embryogenesis by specialization of homologous ADAMTS proteases: insights on collagen biosynthesis and dermatosparaxis. Development. 2006 Apr;133(8):1587-96
1*	J:60156 Lee K, Lanske B, Karaplis AC, Deeds JD, Kohno H, Nissenson RA, Kronenberg HM, Segre GV, Parathyroid hormone-related peptide delays terminal differentiation of chondrocytes during endochondral bone development. Endocrinology. 1996 Nov;137(11):5109-18
1	J:50394 Lefebvre V, Li P, de Crombrugghe B, A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene. EMBO J. 1998 Oct 1;17(19):5718-33
1	J:161784 Lyashenko N, Weissenbock M, Sharir A, Erben RG, Minami Y, Hartmann C, Mice lacking the orphan receptor ror1 have distinct skeletal abnormalities and are growth retarded. Dev Dyn. 2010 Aug;239(8):2266-77
1	J:134987 Mak KK, Kronenberg HM, Chuang PT, Mackem S, Yang Y, Indian hedgehog signals independently of PTHrP to promote chondrocyte hypertrophy. Development. 2008 Jun;135(11):1947-56
1	J:214967 Mangiavini L, Merceron C, Araldi E, Khatri R, Gerard-O'Riley R, Wilson TL, Rankin EB, Giaccia AJ, Schipani E, Loss of VHL in mesenchymal progenitors of the limb bud alters multiple steps of endochondral bone development. Dev Biol. 2014 Sep 1;393(1):124-36
1	J:332099 Maruyama T, Hasegawa D, Valenta T, Haigh J, Bouchard M, Basler K, Hsu W, GATA3 mediates nonclassical beta-catenin signaling in skeletal cell fate determination and ectopic chondrogenesis. Sci Adv. 2022 Dec 2;8(48):eadd6172
1	J:339245 Maruyama T, Jiang M, Hsu W, Gpr177, a novel locus for bone mineral density and osteoporosis, regulates osteogenesis and chondrogenesis in skeletal development. J Bone Miner Res. 2013 May;28(5):1150-9
1	J:153980 Matsushita T, Chan YY, Kawanami A, Balmes G, Landreth GE, Murakami S, Extracellular signal-regulated kinase 1 (ERK1) and ERK2 play essential roles in osteoblast differentiation and in supporting osteoclastogenesis. Mol Cell Biol. 2009 Nov;29(21):5843-57
1	J:210363 Mizuhashi K, Kanamoto T, Moriishi T, Muranishi Y, Miyazaki T, Terada K, Omori Y, Ito M, Komori T, Furukawa T, Filamin-interacting proteins, Cfm1 and Cfm2, are essential for the formation of cartilaginous skeletal elements. Hum Mol Genet. 2014 Jun 1;23(11):2953-67
1	J:186322 Morimoto R, Yamamoto A, Akimoto Y, Obinata A, Homeoprotein Hex is expressed in mouse developing chondrocytes. J Biochem. 2011 Jul;150(1):61-71
1	J:316165 Nakamura E, Hata K, Takahata Y, Kurosaka H, Abe M, Abe T, Kihara M, Komori T, Kobayashi S, Murakami T, Inubushi T, Yamashiro T, Yamamoto S, Akiyama H, Kawaguchi M, Sakata N, Nishimura R, Zfhx4 regulates endochondral ossification as the transcriptional platform of Osterix in mice. Commun Biol. 2021 Nov 3;4(1):1258
1*	J:22321 Neuhaus H, Bettenhausen B, Bilinski P, Simon-Chazottes D, Guenet JL, Gossler A, Etl2, a novel putative type-I cytokine receptor expressed during mouse embryogenesis at high levels in skin and cells with skeletogenic potential. Dev Biol. 1994 Dec;166(2):531-42
1*	J:14821 Ng LJ, Tam PP, Cheah KS, Preferential expression of alternatively spliced mRNAs encoding type II procollagen with a cysteine-rich amino-propeptide in differentiating cartilage and nonchondrogenic tissues during early mouse development. Dev Biol. 1993 Oct;159(2):403-17
1*	J:38926 Ng LJ, Wheatley S, Muscat GE, Conway-Campbell J, Bowles J, Wright E , Bell DM , Tam PP , Cheah KS , Koopman P, SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse. Dev Biol. 1997 Mar 1;183(1):108-21
1*	J:317046 Niebler S, Schubert T, Hunziker EB, Bosserhoff AK, Activating enhancer binding protein 2 epsilon (AP-2epsilon)-deficient mice exhibit increased matrix metalloproteinase 13 expression and progressive osteoarthritis development. Arthritis Res Ther. 2015 May 12;17:119
1	J:316655 Oh SK, Shin JO, Baek JI, Lee J, Bae JW, Ankamerddy H, Kim MJ, Huh TL, Ryoo ZY, Kim UK, Bok J, Lee KY, Pannexin 3 is required for normal progression of skeletal development in vertebrates. FASEB J. 2015 Nov;29(11):4473-84
1*	J:157005 Park J, Zhang JJ, Moro A, Kushida M, Wegner M, Kim PC, Regulation of Sox9 by Sonic Hedgehog (Shh) is essential for patterning and formation of tracheal cartilage. Dev Dyn. 2010 Feb;239(2):514-26
1	J:238878 Ray A, Singh PN, Sohaskey ML, Harland RM, Bandyopadhyay A, Precise spatial restriction of BMP signaling is essential for articular cartilage differentiation. Development. 2015 Mar 15;142(6):1169-79
1	J:149460 Rokutanda S, Fujita T, Kanatani N, Yoshida CA, Komori H, Liu W, Mizuno A, Komori T, Akt regulates skeletal development through GSK3, mTOR, and FoxOs. Dev Biol. 2009 Apr 1;328(1):78-93
1	J:306205 Ruengsinpinya L, Murakami T, Nakamura E, Takahata Y, Hata K, Nakaminami Y, Okae H, Nishimura R, G protein subunit beta1 is an important mediator of the late stage of endochondral ossification. Biochem Biophys Res Commun. 2020 Nov 26;533(1):90-96
1	J:153077 Satake H, Ito K, Takahara M, Furukawa T, Takagi M, Ogino T, Shinomura T, Spatio-temporal expression of activating transcription factor 5 in the skeletal development of mouse limb. Dev Growth Differ. 2009 Sep;51(7):669-76
1*	J:207837 Schmid R, Bosserhoff AK, Redundancy in regulation of chondrogenesis in MIA/CD-RAP-deficient mice. Mech Dev. 2014 Feb;131:24-34
1*	J:88955 Schwabe GC, Trepczik B, Suring K, Brieske N, Tucker AS, Sharpe PT, Minami Y, Mundlos S, Ror2 knockout mouse as a model for the developmental pathology of autosomal recessive Robinow syndrome. Dev Dyn. 2004 Feb;229(2):400-10
1*	J:71996 Selleri L, Depew MJ, Jacobs Y, Chanda SK, Tsang KY, Cheah KS, Rubenstein JL, O'Gorman S, Cleary ML, Requirement for Pbx1 in skeletal patterning and programming chondrocyte proliferation and differentiation. Development. 2001 Sep;128(18):3543-57
1*	J:83132 Settle SH Jr, Rountree RB, Sinha A, Thacker A, Higgins K, Kingsley DM, Multiple joint and skeletal patterning defects caused by single and double mutations in the mouse Gdf6 and Gdf5 genes. Dev Biol. 2003 Feb 1;254(1):116-30
1*	J:117221 Shibukawa Y, Young B, Wu C, Yamada S, Long F, Pacifici M, Koyama E, Temporomandibular joint formation and condyle growth require Indian hedgehog signaling. Dev Dyn. 2007 Feb;236(2):426-34
1*	J:96466 Singh MK, Petry M, Haenig B, Lescher B, Leitges M, Kispert A, The T-box transcription factor Tbx15 is required for skeletal development. Mech Dev. 2005 Feb;122(2):131-44
1	J:95959 Smith N, Dong Y, Lian JB, Pratap J, Kingsley PD, van Wijnen AJ, Stein JL, Schwarz EM, O'keefe RJ, Stein GS, Drissi MH, Overlapping expression of Runx1(Cbfa2) and Runx2(Cbfa1) transcription factors supports cooperative induction of skeletal development. J Cell Physiol. 2005 Apr;203(1):133-43
1*	J:80666 Smits P, Li P, Mandel J, Zhang Z, Deng JM, Behringer RR, de Croumbrugghe B, Lefebvre V, The transcription factors L-Sox5 and Sox6 are essential for cartilage formation. Dev Cell. 2001 Aug;1(2):277-90
1	J:119030 Spater D, Hill TP, O'sullivan RJ, Gruber M, Conner DA, Hartmann C, Wnt9a signaling is required for joint integrity and regulation of Ihh during chondrogenesis. Development. 2006 Aug;133(15):3039-49
1*	J:134001 Surmann-Schmitt C, Dietz U, Kireva T, Adam N, Park J, Tagariello A, Onnerfjord P, Heinegard D, Schlotzer-Schrehardt U, Deutzmann R, von der Mark K, Stock M, Ucma, a novel secreted cartilage-specific protein with implications in osteogenesis. J Biol Chem. 2008 Mar 14;283(11):7082-93
1	J:176532 Sylva M, Li VS, Buffing AA, van Es JH, van den Born M, van der Velden S, Gunst Q, Koolstra JH, Moorman AF, Clevers H, van den Hoff MJ, The BMP antagonist follistatin-like 1 is required for skeletal and lung organogenesis. PLoS One. 2011;6(8):e22616
1	J:336752 Taieb M, Ghannoum D, Barre L, Ouzzine M, Xylosyltransferase I mediates the synthesis of proteoglycans with long glycosaminoglycan chains and controls chondrocyte hypertrophy and collagen fibers organization of in the growth plate. Cell Death Dis. 2023 Jun 9;14(6):355
1*	J:45575 Takagi T, Moribe H, Kondoh H, Higashi Y, DeltaEF1, a zinc finger and homeodomain transcription factor, is required for skeleton patterning in multiple lineages. Development. 1998 Jan;125(1):21-31
1	J:314589 Takahata Y, Hagino H, Kimura A, Urushizaki M, Kobayashi S, Wakamori K, Fujiwara C, Nakamura E, Yu K, Kiyonari H, Bando K, Murakami T, Komori T, Hata K, Nishimura R, Smoc1 and Smoc2 regulate bone formation as downstream molecules of Runx2. Commun Biol. 2021 Oct 19;4(1):1199
1	J:277380 Telley L, Agirman G, Prados J, Amberg N, Fievre S, Oberst P, Bartolini G, Vitali I, Cadilhac C, Hippenmeyer S, Nguyen L, Dayer A, Jabaudon D, Temporal patterning of apical progenitors and their daughter neurons in the developing neocortex. Science. 2019 May 10;364(6440)
1*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1	J:68793 Ueta C, Iwamoto M, Kanatani N, Yoshida C, Liu Y, Enomoto-Iwamoto M, Ohmori T, Enomoto H, Nakata K, Takada K, Kurisu K, Komori T, Skeletal malformations caused by overexpression of Cbfa1 or its dominant negative form in chondrocytes. J Cell Biol. 2001 Apr 2;153(1):87-100
1*	J:307862 Wilkerson BA, Zebroski HL, Finkbeiner CR, Chitsazan AD, Beach KE, Sen N, Zhang RC, Bermingham-McDonogh O, Novel cell types and developmental lineages revealed by single-cell RNA-seq analysis of the mouse crista ampullaris. Elife. 2021 May 18;10:e60108
1*	J:146657 Witte F, Dokas J, Neuendorf F, Mundlos S, Stricker S, Comprehensive expression analysis of all Wnt genes and their major secreted antagonists during mouse limb development and cartilage differentiation. Gene Expr Patterns. 2009 Apr;9(4):215-23
1	J:320311 Yang L, Gu S, Ye W, Song Y, Chen Y, Augmented Indian hedgehog signaling in cranial neural crest cells leads to craniofacial abnormalities and dysplastic temporomandibular joint in mice. Cell Tissue Res. 2016 Apr;364(1):105-15
1*	J:81355 Yang Y, Topol L, Lee H, Wu J, Wnt5a and Wnt5b exhibit distinct activities in coordinating chondrocyte proliferation and differentiation. Development. 2003 Mar;130(5):1003-15
1	J:281275 Yao Q, Khan MP, Merceron C, LaGory EL, Tata Z, Mangiavini L, Hu J, Vemulapalli K, Chandel NS, Giaccia AJ, Schipani E, Suppressing Mitochondrial Respiration Is Critical for Hypoxia Tolerance in the Fetal Growth Plate. Dev Cell. 2019 Jun 3;49(5):748-763.e7
1	J:221866 Yoshida M, Hata K, Takashima R, Ono K, Nakamura E, Takahata Y, Murakami T, Iseki S, Takano-Yamamoto T, Nishimura R, Yoneda T, The transcription factor Foxc1 is necessary for Ihh-Gli2-regulated endochondral ossification. Nat Commun. 2015;6:6653
1*	J:75934 Zelzer E, McLean W, Ng YS, Fukai N, Reginato AM, Lovejoy S, D'Amore PA, Olsen BR, Skeletal defects in VEGF(120/120) mice reveal multiple roles for VEGF in skeletogenesis. Development. 2002 Apr;129(8):1893-904
1	J:104605 Zhang R, Murakami S, Coustry F, Wang Y, de Crombrugghe B, Constitutive activation of MKK6 in chondrocytes of transgenic mice inhibits proliferation and delays endochondral bone formation. Proc Natl Acad Sci U S A. 2006 Jan 10;103(2):365-70
1	J:286157 Zheng C, Lin X, Xu X, Wang C, Zhou J, Gao B, Fan J, Lu W, Hu Y, Jie Q, Luo Z, Yang L, Suppressing UPR-dependent overactivation of FGFR3 signaling ameliorates SLC26A2-deficient chondrodysplasias. EBioMedicine. 2019 Feb;40:695-709
1	J:200718 Zhou W, Zhu H, Zhao J, Li H, Wan Y, Cao J, Zhao H, Yu J, Zhou R, Yao Y, Zhang L, Wang L, He L, Ma G, Yao Z, Guo X, Misexpression of Pknox2 in mouse limb bud mesenchyme perturbs zeugopod development and deltoid crest formation. PLoS One. 2013;8(5):e64237
1	J:154920 Zirzow S, Ludtke TH, Brons JF, Petry M, Christoffels VM, Kispert A, Expression and requirement of T-box transcription factors Tbx2 and Tbx3 during secondary palate development in the mouse. Dev Biol. 2009 Dec 15;336(2):145-55